Synthetic cannabinoids, often known as “Spice,” are increasingly embraced by adults aged 18 to 40 worldwide. Their rise in popularity, particularly noted as we entered 2024, highlights a continued interest in exploring alternative experiences. Synthetic cannabinoids are laboratory-created compounds designed to mimic the euphoric and relaxing effects similar to those of natural cannabinoids, including THC and CBGA. These substances have been crafted to offer legal avenues for euphoria without the legality issues or detectability in drug tests that traditional substances might entail.


Despite challenges, including regulatory scrutiny, manufacturers globally, especially in China and worldwide, have continued to innovate, creating new, potent synthetic cannabinoids. This ensures enthusiasts can still access legal alternatives for their desired experiences.


This article, derived from forum research including platforms like Reddit, is independently crafted and does not reflect Flight AMS’s views or offer advice. It discusses “noids,” “chems,” and “legal highs” — terms referring to synthetic cannabinoids used in products like Herbal Incense and C-liquids.


Popular New Synthetic Cannabinoids and Their Positive Effects



  • FUB-AMB: Previously a favorite due to its potency, though less common now due to regulations.

  • 5F-MDMB-2201: Offers a unique, intense experience reminiscent of psychedelics like LSD and psilocybin.

  • SGT-151: Known for its gentle effects, it remains popular and legal in many areas.

  • 5f-SGT-151: Highly potent, providing strong experiences.

  • NM-2201: Favored for its mild effects without adverse side effects.

  • FAB-144: Similar to NM-2201, it offers a mild, enjoyable experience akin to natural cannabis.

  • 5f-ADB: Noted for its significant potency and immersive experiences.

  • 5-CL-ADB-A: Known for its strong, sedative effects, ideal for creating potent vape juices.

  • 4f-ADB: One of the most robust options available, offering powerful experiences.

  • ADB-FUBINACA: Valued for its positive effects and versatility in making herbal blends and C-liquids.

  • AB-CHMINACA: Provides a pleasant high when used in moderation.

  • JWH-210: Offers euphoric effects similar to cannabis, without disrupting sleep or appetite.

  • JWH-018: Known for its unique, trippy experiences.

  • 5C-AKB-48: Distinguished by its sedative properties and extended duration.

  • THJ-018: Mild and likened to cannabis, it’s praised for its balanced effects.


The landscape of synthetic cannabinoids continues to evolve, with many new compounds available that range from mild to strong. Most of these new substances remain legal in various jurisdictions, providing alternatives to traditional, now-restricted substances.


Disclaimer: The content above is provided by an independent writer based on forum research and does not represent the views of Flight AMS. It is not intended as advice of any kind. The products mentioned are not for human consumption, require an age of 18+ for purchase, and are intended solely for laboratory research.